RIFAXIMIN-MEDIATED GUT MICROBIOTA REGULATION MODULATES THE FUNCTION OF MICROGLIA AND PROTECTS AGAINST CUMS-INDUCED DEPRESSION-LIKE BEHAVIORS IN ADOLESCENT RAT

Abstract Background Chronic unpredictable mild stress (CUMS) can not only lead to depression-like behavior but also change the composition of the gut microbiome.Regulating the gut microbiome can have an antidepressant effect, but the mechanism by which it improves depressive symptoms is not clear.Short-chain fatty acids shoes (SCFAs) are small mole

Glioblastoma is a solid, infiltrating, and the most frequent highly malignant primary brain tumor.Our aim was to find the correlation between sex, age, preoperative Karnofsky performance status (KPS), presenting with seizures, and extent of resection (EOR) with overall survival (OS), progression-free survival (PFS), and Balms postoperative KPS, alo

In the protein nutrition strategy of middle-aged and elderly people, some believe that low protein is good for health, while others believe high protein is good for health.Facing the contradictory situation, the following hypothesis is proposed.There is a process of change from lower to higher ratio of protein nutritional requirements that are good

Study Region: We interrogate the water resources of the Upper Kaligandaki River Basin (UKGRB), in the shoes remote Mustang District of northwestern Nepal.The Nepal Himalayas are a major reservoir of freshwater; yet the impediments to its exploitation by local inhabitants are manifold, including weak governance structures, steep and irregular terrai

The subject, which is in the philosophical works of Y.Krysteva and in the following philosophical Joggers interpretations of her work is explored in the article.There is shown, that Y.Krysteva strives to preserve both the subject and its functioning as a social practice.The expedience of the rethinking of the concept of transcendental subject and a